Patrick T. Ellinor, MD, PhD

The goal of our laboratory work is to use genetics to elucidate the molecular basis underlying abnormalities of the heart rhythm and heart function. Much of our recent work has focused atrial fibrillation which is the most common arrhythmia. To identify novel pathways for atrial fibrillation we are using a broad range of techniques including population genetics, electrophysiology, and animal models of arrhythmias. 

This work in turn led the establishment of the AFGen Consortium, an international group of investigators studying the genetics of atrial fibrillation. In the ensuing years, we have led large-scale genetic analyses for atrial fibrillation and many other cardiovascular diseases. Our work now spans a wide range of topics centered on cardiovascular disease genetics, mechanisms, single cell sequencing, and therapeutic development.

Contact Info:

Massachusetts General Hospital
Cardiovascular Research Center
Simches Research Building
185 Cambridge Street, 3.181
Boston, MA 02114


617-724-8729

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Ellinor Lab

Publications: