Steven A. Lubitz, MD, MPH
Cardiac arrhythmias are a leading cause of morbidity and sudden death, and collectively constitute a substantial public health problem. We are focused on understanding the inherited basis of cardiac arrhythmias and applying discoveries to improve outcomes in patients with these conditions. Our research spans disciplines involving human genetics and epidemiology. Several areas of active investigation include:
Determining the genetic basis of heritable arrhythmias: Using genotyping and sequencing techniques, we aim to determine genetic factors that underlie atrial fibrillation and arrhythmias associated with sudden cardiac arrest, including the long QT syndrome, Brugada syndrome, arrhythmogenic ventricular cardiomyopathy, catecholaminergic polymorphic ventricular tachycardia, dilated cardiomyopathy, left ventricular noncompaction, and others.
Characterizing the long-term course of atrial fibrillation: By characterizing the long-term course of patients with atrial fibrillation, and by identifying factors that associate with clinical outcomes, we aim to identify strategies to improve the care of patients with this common arrhythmia.
Improving risk stratification and treatment of individuals with inherited arrhythmias: We are studying approaches to tailor the care of patients with inherited arrhythmia conditions in order to minimize the risk of sudden cardiac arrest.
Massachusetts General Hospital
Cardiovascular Research Center
149 13th Street, 4.302
Charlestown, MA 02129