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Jason Roh, MD, MHS

Jason Roh, MD, MHS

Massachusetts General Hospital

Assistant Professor of Medicine
Harvard Medical School

Massachusetts General Hospital
Cardiovascular Research Center
Simches Research Building, Room 3.186
185 Cambridge Street
Boston, MA 02114

Dr. Jason Roh is an Assistant Professor at Harvard Medical School and a Beeson Scholar of the National Institute on Aging. Dr. Roh runs the interdisciplinary geriatric-cardiology clinic at MGH, and is a member of the Sections of Cardiovascular Medicine, Preventive Cardiology, Geriatrics, and Echocardiography. His lab in the CVRC focuses on the role of aging biology in cardiovascular disease.

Age has long been known to be a dominant risk factor for nearly all types of cardiovascular disease. However, how aging contributes to heart disease and whether it can be effectively modified to treat or prevent disease are unclear. Our group is addressing these questions by using geroscience approaches to identify mechanisms of aging biology associated with cardiovascular disease that can potentially be used as therapeutic targets. We utilize integrative approaches that incorporate high-throughput -omics technology for discovery with rigorous causal and functional assessments in animal models. Our team is actively investigating the role of aging biology in a wide spectrum of diseases, including heart failure, atrial fibrillation, frailty, and pregnancy-related cardiovascular diseases.

Dr. Roh received his BA from Amherst College in Biology (2001) and his MD and MHS from Yale University (2008). He completed his internship and residency at Brigham and Women’s Hospital (2011), and his general cardiology fellowship, advanced echocardiography, and postdoctoral training in molecular cardiology at Beth Israel Deaconess Medical Center (2015). In January 2021, he joined the faculty of the CVRC to establish a cardiovascular aging biology laboratory.

Research Areas
Cardiac Physiology and Disease
Chemical Biology and Therapeutics

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