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Jesse David Roberts Jr., MD

Jesse David Roberts Jr., MD

Director, Newborn Research
Massachusetts General Hospital for Children

Associate Professor of Anesthesia
Harvard Medical School

Massachusetts General Hospital
Cardiovascular Research Center
149 13th Street, 4.214
Charlestown, MA 02129

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Lung injury in newborns and infants often causes abnormal lung development and function. For example, in infants with some forms of congenital heart disease, lung injury causes an abnormal increase in the smooth muscle cells in the blood vessels of the lung periphery and, in part through this mechanism, causes pulmonary hypertension and heart failure. In premature infants, lung injury associated with life-sustaining ventilation of the lungs with oxygen can decrease the development of the peripheral lung and cause bronchopulmonary dysplasia, a chronic lung disease. The long-term goals of my laboratory are to explore the fundamental mechanisms of lung injury and to develop novel therapies for pulmonary diseases in newborns and infants.

Research Areas
Development & Regeneration
Vascular Biology and Metabolism