Djenoune L, Mahamdeh M, Truong TV, Nguyen CT, Fraser SE, Brueckner M, Howard J, Yuan S.
Cilia as Cellular Force Sensors During Embryogenesis.
Science 2023 Jan 6;379(6627):71-78. PMID: 36603098.
“Nearly 25 years of work by numerous groups have shown that cilia and flow in the organizer are absolutely essential for establishing body left-right asymmetry”, says Shiaulou Yuan, PhD, an investigator in the Cardiovascular Research Center at Massachusetts General Hospital and assistant professor of medicine at Harvard Medical School, and senior author of the study. “But we haven’t had the right tools or techniques to definitively study how this all works.”
