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Steven A. Lubitz, MD, MPH

Cardiac Electrophysiologist
Massachusetts General Hospital

Associate Professor of Medicine
Harvard Medical School

Massachusetts General Hospital
Cardiovascular Research Center
Simches Research Building
185 Cambridge Street, 3.188
Boston, MA 02114

Cardiac arrhythmias are a leading cause of morbidity and sudden death, and collectively constitute a substantial public health problem. We are focused on understanding the mechanisms of arrhythmias, identifying individuals at risk, and intervening to improve health outcomes. Our group comprises a large and collaborative multi-disciplinary team focused on improving cardiovascular health by leveraging human genetics, prediction modeling, and clinical trials. Several areas of active investigation include:

Determining the genetic basis of arrhythmias
Using genotyping and sequencing techniques, we aim to determine genetic factors that underlie atrial fibrillation, bradyarrhythmias, and sudden cardiac arrest. We leverage rare disease collections and large-scale biorepositories to perform genetic discovery.

Identifying individuals at risk for arrhythmias and related morbidity 
By curating datasets including electronic health record data and imaging data, we study factors associated with onset of cardiovascular disease. We use a variety of conventional and novel statistical methods to inform risk assessment.

Improving treatment of individuals with or at risk for arrhythmias
We seek to determine whether specific interventions will improve outcomes and efficiency of care delivery. We are examining digital technology, including wearables, in large-scale clinical trials to screen for atrial fibrillation.

Research Areas
Cardiac Physiology and Disease

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